![]() ReadyToProcess Capto S ImpAct columns,1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation. Process Characterization Kit Capto S ImpAct, designed for studying the potential impact that resin ligand density might have on the process outcome. Typical packing factors for Capto S, Capto Q, and Capto DEAE in different solutions for optimal bed performance where the bed is consolidated at 3060 cm/h Solution Capto Q Capto S Capto DEAE Water 1.10 1.10 1.10 20 ethanol 1.10 10 mM NaCl 1.17 1.17 1.17 20 ethanol with 0.2 M sodium acetate N/A 1. HiTrap Capto S ImpAct columns, for easy use with a syringe, peristaltic pump, or chromatography system. Lab scale: prepacked for automated purification and analysis Lab scale: prepacked for manual purification The medium has a polymer-grafted ligand composed of a mix of two different building blocks, a. HiScreen Capto S ImpAct columns, optimized for method and process development. Capto S ImpAct is a strong cation exchange (CIEX) medium.PreDictor Capto S ImpAct RoboColumn™ units, miniaturized columns for high-throughput process development.PreDictor Capto S ImpAct filter plates, 96-well plates for high-throughput screening or process development.Backpressure is nevertheless below 3 bar (0.3 MPa, 43.5 psi). Prepacked columns and other formatsĬapto S ImpAct resin is available in the following formats: Process development scale: prepacked Capto SP ImpRes SP Sepharose High Performance High-throughput processing improves productivity The rigidity of Capto ImpRes media permits high flow velocities at least 220 cm/h for Capto SP ImpRes and Capto Q ImpRes in a 1 m diameter column with 20 cm bed height. Based on the well-established Capto base matrix, it provides many opportunities for improved productivity and straightforward process development. Suited to industrial scale applicationsĬapto S ImpAct is a BioProcess chromatography resin developed for large-scale purification of biopharmaceutical proteins. The high binding capacity and resolution of Capto S ImpAct, combined with the ability to run at high flow rates and bed heights, increase productivity and flexibility in process design. 217.00 - 643.00 Specifications View More Specs Products 2 Description Specifications Description High binding capacity, > 100 mg MAb/mL medium. Capto S ImpAct is a strong cation exchange chromatography medium (resin) developed for polishing of monoclonal antibodies (MAbs) and other biomolecules. Security of supply and comprehensive regulatory supportĬapto S ImpAct is delivered in different bulk sizes as well as in many prepacked formats such as PreDictor™ 96-well filter plates, PreDictor RoboColumn™, HiTrap™, and HiScreen™ columns.The high-flow characteristics of Capto resin allow for good pressure-flow properties. Capto S ImpAct is a strong cation exchange chromatography medium (resin) developed for polishing of monoclonal antibodies (MAbs) and other biomolecules. GE Healthcare Life Sciences Capto S ImpAct cation exchange chromatography medium is designed for efficient and flexible purification of monoclonal.High productivity, enabling cost-efficient manufacturing.Large operational window of flow rates and bed heights for easy optimization and scale up.High-resolution for efficient aggregate removal at high sample loads. ![]() High binding capacity, more than 100 mg MAb/mL medium.The ability to run at both high flow rates and bed heights combines with these attributes to increase productivity and flexibility in process design. The small bead size for high resolution, in combination with the novel extended-surface ligands, supports high dynamic binding capacity at high sample loads. The high-flow characteristics of the Capto base matrix enables excellent pressure-flow properties. Part of the established Capto platform of high-performance chromatography media, Capto S ImpAct offers both high binding capacity and high resolution at high sample loads. Capto S ImpAct is a strong cation exchanger for the intermediate and polishing steps when purifying MAbs and a wide range of other biomolecules.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |